Immunology of Leishmaniasis and Future Prospective of Vaccines
نویسندگان
چکیده
Rakesh Sehgal1, Kapil Goyal1, Rupinder Kanwar2, Alka Sehgal3 and Jagat R. Kanwar2 1Department of Parasitology, Postgraduate Institute of Medical Education & Research, Chandigarh, 2Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (LIMBR), Centre for Biotechnology and Interdisciplinary Biosciences (BioDeakin), Institute for Technology & Research Innovation (ITRI), Deakin University, Geelong, Technology Precinct (GTP), Waurn Ponds, Geelong, Victoria, 3 Government Medical College & Hospital, Sector 32, Chandigarh, 1,3India 2Australia
منابع مشابه
Expression of Recombinant Heat-Shock Protein 70 of MCAN/IR/96/LON-49, a Tool for Diagnosis and Future Vaccine Research
Background: Heat shock protein 70 (HSP70) is present in all organisms studied so far, and is a major immunogen in infections caused by pathogens including Leishmania spp. Objective: The aim of this study was to clone and express HSP70 from L. infantum strain MCAN/IR/96/LON-49 and evaluate antibody response against HSP70 in visceral leishmaniasis (VL). Methods: The L. infantum HSP70 gene segment...
متن کاملThe role of ISCOMATRIX bilayer composition to induce a cell mediated immunity and protection against leishmaniasis in BALB/c mice
Objective(s):Development of new generation of vaccines against leishmaniasis is possible because long-term protection is usually seen after recovery from cutaneous leishmaniasis. ISCOMATRIX is particulate antigen delivery system composed of antigen, cholesterol, phospholipid and saponin. In this study, the role of ISCOMATRIX bilayer composition made by different phase transition temperature (Tc...
متن کاملکاربرد نانوحامل ها در ایمنی زایی علیه بیماری ها
The relationship between nanotechnology and immunology can be evaluated from different aspects. The application of nanotechnology and immunology is widespread and has important features in medical biotechnology. Delivery of active immunological compounds to the target sites using nano-carriers is one of the issues related to nanotechnology and immunology. Moreover, successful application of nan...
متن کاملPlant-derived compounds in treatment of leishmaniasis
Leishmaniasis is a neglected public health problem caused by the protozoan species belonging to the genus Leishmania affecting mostly the poor populations of developing countries. The causative organism is transmitted by female sandflies. Cutaneous, mucocutaneous, and visceral clinical manifestations are the most frequent forms of leishmaniasis. Chemotherapy still relies on the use of pentavale...
متن کاملA short review on immunology of Leishmaniasis
Among the countless examples of interspecific interactions in biology, surely non-could be more interesting than which established between host animals and their specific parasites. The members of the genus Leishmania are peculiar obligate intracellular protozoans in that they proliferate in the enzyme rich phagolysosomes, an organelle which is essential component of all defence reactions of an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012